Oral supplementations with l-glutamine or l-alanyl-l-glutamine do not change metabolic alterations induced by long-term high-fat diet in the B6.129F2/J mouse model of insulin resistance
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منابع مشابه
Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,15N]glutamine or L-[2,15N]glutamine in mice.
Previously, we observed increased plasma arginine (ARG) concentrations after glutamine (GLN)-enriched diets, in combination with clinical benefits. GLN delivers nitrogen for ARG synthesis, and the present study was designed to quantify the interorgan relationship of exogenous L-GLN or GLN dipeptide, by enteral or parenteral route, contributing to intestinal citrulline (CIT) and renal de novo AR...
متن کاملIntestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,N]glutamine or L-[2,N]glutamine in mice
Boelens, Petra G., Paul A. M. van Leeuwen, Cornelis H. C. Dejong, and Nicolaas E. P. Deutz. Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,N]glutamine or L-[2,N]glutamine in mice. Am J Physiol Gastrointest Liver Physiol 289: G679–G685, 2005. First published July 28, 2005; doi:10.1152/ajpgi.00026.2005.—Previously, we observed ...
متن کاملMouse embryo development following IVF in media containing either L-glutamine or glycyl-L-glutamine.
BACKGROUND The development of the mouse zygote following fertilization in vitro in a KSOM-type medium containing either L-glutamine or glycyl-L-glutamine has been examined, and compared with the development of mouse zygotes produced by natural fertilization. METHODS Mouse IVF, embryo culture and embryo transfer. RESULTS Fertilization rates, development to the blastocyst stage, implantation ...
متن کاملL-Alanyl-Glutamine Attenuates Oxidative Stress in Liver Transplantation Patients.
BACKGROUND Ischemia/reperfusion injury during liver transplantation can cause severe damage to the graft. The objective of this randomized, double-blind study was to evaluate the possible protective effects of L-alanyl-glutamine on the liver graft. METHODS The sample included 33 patients from a liver transplantation service in Northeastern Brazil. Before cold ischemia, the patients received 5...
متن کاملL-glutamine as an insulin secretagogue
We have carried out a detailed examination of L-glutamine metabolism in rat islets in order to elucidate the paradoxical failure of L-glutamine to stimulate insulin secretion. L-Glutamine was converted by isolated islets into GABA (γ -aminobutyric acid), L-aspartate and L-glutamate. Saturation of the intracellular concentrations of all of these amino acids occurred at approx. 10 mmol/l L-glutam...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biochemistry
سال: 2015
ISSN: 0300-8177,1573-4919
DOI: 10.1007/s11010-015-2597-6